Bacopa Monnieri
Bacopa Monnieri
Purity Levels
Bacosides by HPLC & USP — 20–55% grades (50% standard grade), free of PAHs
Extraction Technologies
Mechotech designs and manufactures turnkey extraction plants for Bacopa monnieri (Brahmi), processing Bacopa herb into an extract standardised to Bacosides A and B by HPLC and USP methods and tested free of polycyclic aromatic hydrocarbons (PAHs) — a residual-contaminant control specific to Bacopa's small-particle, high-surface-area plant matrix. We supply the complete machinery — herb cleaning, milling, hydro-alcoholic extraction, filtration, vacuum concentration, closed-loop solvent recovery, standardisation and drying — to process Bacopa into a consistent extract for the nootropic supplement, pharmaceutical, and Ayurvedic industries. Candidate extraction technologies for bacosides: Counter-Current Extraction (CCE), Ultrasound-Assisted Extraction (UAE), Hybrid Extraction and Microwave-Assisted Extraction (MAE) (4 in total).
Mechotech's Bacopa monnieri plant is engineered around the specific chemistry of the plant's saponin glycosides (Bacosides A and B, quantified together as total bacosides), which require a hydro-alcoholic solvent system to achieve efficient recovery without degrading the dammarane-type triterpenoid backbone. Because dried Bacopa herb is a fine, high-surface-area matrix, the line includes dedicated pre-treatment and filtration stages to control PAH pickup and particulate carryover ahead of standardisation, so the finished extract can be certified free of PAHs alongside its bacoside assay. Built in SS 316L with electropolished product-contact surfaces, PLC-based automation, and full batch documentation, each plant is delivered as a commissioned turnkey system configured to the declared Bacosides by HPLC & USP specification (grades from 20% to 55% achievable).
Technical Specifications
| Product | Bacopa Monnieri Extraction Plant |
|---|---|
| Botanical Name | Bacopa monnieri |
| Feedstock | Bacopa herb |
| Part / Feed Form | Confirm exact plant part / form (to be confirmed with the client) |
| Target Extract | Bacosides |
| Extract Type | Standardised dry extract (powder) |
| Standardisation | Bacosides (A & B) By HPLC & USP, free of PAHs — 20% to 55% grades achievable |
| Extraction Method | Counter-current, UAE, Hybrid, MAE |
| Technology Count | 4 |
| Extraction Conditions | Hydro-alcoholic solvent extraction (closed, jacketed SS 316L extractors) |
| Product-contact Material | SS 316L, electropolished, CIP-cleanable |
| Filtration System | Plate-and-frame filter press with cartridge polish filtration; carbon treatment for PAH/colour control |
| Concentration System | Falling-film / vacuum evaporator with closed-loop solvent recovery |
| Drying System | Spray dryer or vacuum tray dryer |
| Automation | PLC-SCADA with recipe management, batch traceability and production reporting |
| Plant Capacity | Configured to requirement |
| Utility Requirements | Steam, chilled/cooling water, compressed air, soft water, power (project-specific) |
| Compliance | GMP hygienic design; full documentation for qualification |
| Final Product Form | Free-flowing standardised extract powder |
Plant Capacities
| Plant Scale | Herb Throughput | Typical Use |
|---|---|---|
| Pilot | Configured to your feedstock and trial plan | Product development, parameter validation |
| Semi-Commercial | Configured between pilot and commercial scale | Contract manufacturing, scale-up trials |
| Commercial | Configured to raw-material supply and confirmed buyer volume | Export-grade continuous production |
Capacity is configured to raw-material supply and confirmed buyer volume; we recommend a pilot plant to validate bacoside recovery and PAH-control parameters before scaling.
Manufacturing Process
Each extraction method follows a different process — pick a method to see its steps.
Raw-Material Preparation
Bacopa herb is cleaned and size-reduced so bacosides can be reached by the extraction medium; particle size and moisture are set during process development.
Counter-Current Loading
Prepared Bacopa herb is fed into a multi-stage solid–liquid counter-current extractor where fresh ethanol/water or a suitable food-grade solvent meets the most-depleted material.
Counter-Current Extraction
Solvent flows against the solids across stages to draw out bacosides; bed flow and fines management are verified during pilot work.
Extract (Miscella) Collection
The bacosides-bearing miscella is collected from the fresh-feed end while spent solids are discharged from the solvent-entry end.
Concentration & Solvent Recovery
Solvent is removed from the clarified bacosides-bearing extract under vacuum and returned through a solvent-recovery loop; recovery performance is confirmed at pilot scale.
Standardisation & Drying
The bacosides extract is assayed against the declared target specification and dried to a powder, or supplied as a concentrate, according to the requirement.
Raw-Material Preparation
Bacopa herb is cleaned and size-reduced so bacosides can be reached by the extraction medium; particle size and moisture are set during process development.
Slurrying
Prepared Bacopa herb is slurried with ethanol/water or water in the extraction vessel.
Ultrasonic Cavitation
Ultrasound creates cavitation that disrupts the feed tissue and speeds release of bacosides; probe intensity, temperature and filtration behaviour are piloted.
Separation
Spent solids are separated by filtration or centrifugation and the extract is clarified before concentration.
Concentration & Solvent Recovery
Solvent is removed from the clarified bacosides-bearing extract under vacuum and returned through a solvent-recovery loop; recovery performance is confirmed at pilot scale.
Standardisation & Drying
The bacosides extract is assayed against the declared target specification and dried to a powder, or supplied as a concentrate, according to the requirement.
Raw-Material Preparation
Bacopa herb is cleaned and size-reduced so bacosides can be reached by the extraction medium; particle size and moisture are set during process development.
Stage Sequence Selection
A deliberate combined extraction train is used: the sequence of stages is selected for bacosides in pilot screening and each stage is designed separately.
First Assisted Stage
The first stage releases bacosides from the feed under controlled conditions set for that stage.
Second / Combined Stage
The second stage completes recovery of bacosides from the partially extracted material; stage conditions are optimised separately.
Separation & Concentration
Spent solids are removed and the combined extract is clarified and concentrated; solvent is recovered where a solvent is used.
Standardisation & Drying
The bacosides extract is assayed against the declared target specification and dried to a powder, or supplied as a concentrate, according to the requirement.
Raw-Material Preparation
Bacopa herb is cleaned and size-reduced so bacosides can be reached by the extraction medium; particle size and moisture are set during process development.
Medium Mixing
Prepared Bacopa herb is mixed with ethanol/water or water in the microwave extraction vessel.
Microwave Heating & Extraction
Controlled microwave heating drives bacosides out of the feed in a short cycle; heating, moisture, solvent safety and temperature-sensitive targets are controlled, with limits set during process development and pilot validation.
Separation
Spent solids are separated by filtration or centrifugation and the extract is clarified before concentration.
Concentration & Solvent Recovery
Solvent is removed from the clarified bacosides-bearing extract under vacuum and returned through a solvent-recovery loop; recovery performance is confirmed at pilot scale.
Standardisation & Drying
The bacosides extract is assayed against the declared target specification and dried to a powder, or supplied as a concentrate, according to the requirement.
Major Plant Equipment
- Raw material cleaning system
- Hammer mill (size reduction)
- Stainless-steel hydro-alcoholic extraction vessels (jacketed, SS 316L)
- Solvent storage tanks
- Solvent transfer pumps
- Plate-and-frame filter press / pressure leaf filter
- Cartridge polish filters
- Activated-carbon treatment column (PAH/colour control)
- Falling-film / multi-stage vacuum evaporator
- Closed-loop solvent recovery system
- Condensers & vacuum pumps
- Spray dryer / vacuum tray dryer
- CIP (clean-in-place) system
- Storage tanks & finished-product tanks
- PLC-SCADA control panel, electrical MCC & instrumentation
Plant Output
Case Study
Bacopa Monnieri Extraction Plant — 20–55% Bacoside-Standardised Production
See how this plant was engineered and delivered for a real project.
Applications
- Nootropic and cognitive-support supplement capsules and tablets
- Memory and mental-clarity nutraceutical formulations
- Pharmaceutical standardised ingredient supply
- Ayurvedic and traditional medicine preparations (Brahmi formulations)
- Paediatric and geriatric cognitive-wellness supplement blends
- Export to regulated-market ingredient buyers requiring PAH-free certification
Key Features
GMP Hygienic SS 316L Construction
Electropolished SS 316L product-contact surfaces use GMP hygienic design, with CIP operation between batches.
Dedicated PAH-Control Stage
An integrated activated-carbon treatment step targets polycyclic aromatic hydrocarbon reduction, supporting the PAH-free release criterion specific to Bacopa's fine plant matrix.
Closed-Loop Solvent Recovery
Integrated recovery returns the solvent for reuse within the process; recovery performance is established during process development.
Dual-Method Standardisation
In-process and batch-release assay by both HPLC and USP methods are used to check the finished extract against its declared Bacosides A & B specification.
Integrated Drying
A matched spray/vacuum dryer produces a free-flowing, low-moisture powder ready for encapsulation and blending.
Scalable Batch Capacity
Plants are configured to requirement from pilot scale upward, with modular expansion.
Frequently Asked Questions
Does Mechotech supply the complete machinery for Bacopa Monnieri?
What specification can the Bacopa Monnieri plant achieve?
Why is a PAH-free certification specifically relevant for Bacopa extract?
Which plant part or feed form does the Bacopa herb plant process?
What production capacities are available for the Bacopa Monnieri plant?
Which industries use the Bacopa Monnieri plant, and does the plant support GMP qualification?
What is the typical cost and delivery timeline for a Bacopa Monnieri extraction plant?
Which extraction technologies are candidates for Bacopa herb?
How does the Bacopa Monneri extraction process work?
What equipment does the Bacopa Monneri extraction plant include?
Is a pilot trial recommended for Bacopa herb feedstock extraction?
Is Brahmi the same as Centella asiatica?
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