Nano Curcumin — 20-100nm Particle Size
Nano Curcumin — 20-100nm Particle Size
Purity Levels
20-100nm particle size, enhanced bioavailability
Standard curcumin extract is poorly absorbed by the body because of its low water solubility and rapid metabolic clearance. Mechotech's nano curcumin plant reduces particle size to the 20-100nm range using high-pressure homogenisation and nanoprecipitation, producing a formulation with substantially higher bioavailability for pharmaceutical and premium nutraceutical use.
Nano curcumin manufacturing adds a size-reduction and stabilisation stage on top of conventional curcumin extraction. Mechotech's plant integrates the standard extraction/concentration process with high-pressure homogenisation, nanoprecipitation, or microfluidisation (selected to match your target particle-size distribution and stabiliser system), followed by particle-size verification and lyophilisation or spray-drying to a stable nano powder. All product-contact surfaces are SS 316L, WHO-GMP compliant, and the system is delivered commissioned and performance-verified.
Manufacturing Process
Curcumin Extraction & Standardisation
Turmeric rhizome is extracted and standardised to high-purity curcuminoid extract using the same closed-loop SS 316L extraction and solvent-recovery process as our standard curcumin plant.
Nanoformulation
The standardised extract is reduced to a 20-100nm particle size via high-pressure homogenisation, nanoprecipitation, or microfluidisation, with a food/pharma-grade stabiliser system (e.g. phospholipid or polymer encapsulation) selected for your target application.
Particle Size Verification
In-line and batch dynamic light scattering (DLS) confirms particle size distribution is within the declared 20-100nm range before proceeding to drying.
Stabilisation & Drying
The nano-suspension is spray-dried or lyophilised (freeze-dried) to a stable, redispersible powder, preserving the nano particle size through the drying step.
Quality Control
Batch release testing covers particle size distribution, curcuminoid assay, residual solvent, heavy metals, microbial load, and moisture, with full certificate of analysis.
Applications
- High-bioavailability nutraceutical capsules and softgels
- Pharmaceutical formulations requiring enhanced absorption
- Premium functional food and beverage fortification
- Cosmeceutical and topical delivery formulations
- Clinical and research-grade curcumin supply
- Export to regulated markets requiring documented bioavailability data
Key Features
20-100nm Particle Size Control
In-line DLS monitoring holds the finished product within the declared nano particle-size range, batch after batch.
GMP-Compliant SS 316L Construction
Electropolished SS 316L product-contact surfaces meet WHO-GMP and Schedule M requirements, with CIP operation between batches.
Configurable Nanoformulation Method
High-pressure homogenisation, nanoprecipitation, or microfluidisation is selected and engineered around your target particle size and stabiliser system.
Stable, Redispersible Powder Output
Spray-drying or lyophilisation is matched to the formulation to preserve nano particle size through to the finished powder.
Scalable Batch Capacity
Plants are configured from pilot scale for formulation development to commercial batch sizes with modular expansion.
Frequently Asked Questions
Why does curcumin need to be nano-formulated?
What nanoformulation methods does Mechotech's plant support?
How is the 20-100nm particle size verified?
Can the same plant produce standard and nano curcumin?
What batch capacities are available?
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