Griffonia simplicifolia Extract
Griffonia simplicifolia Extract
Purity Levels
5-HTP By HPLC 20% to 99%
Mechotech designs and manufactures turnkey herbal extraction plants for Griffonia simplicifolia, the West African climbing shrub whose seed is the world's principal commercial natural source of 5-hydroxytryptophan (5-HTP), standardised to 5-HTP By HPLC 20% to 99%. Unlike most botanical actives that require enzymatic or metabolic conversion downstream, Griffonia seed contains 5-HTP directly as a free amino acid, which makes the target compound itself highly water-soluble, thermally sensitive and prone to oxidative degradation if extraction and drying are not tightly controlled. We supply the complete machinery — seed cleaning, milling, aqueous/hydro-alcoholic extraction, filtration, vacuum concentration, closed-loop solvent recovery, HPLC-verified standardisation and drying — to process Griffonia seed into a consistent 5-HTP extract for the nutraceutical and dietary-supplement industries. The 95% 5-HTP By HPLC grade, listed in the catalogue as Hydroxin, is covered on this page as part of the 20% to 99% range.
Mechotech's Griffonia simplicifolia plant is engineered around the specific handling requirements of a free amino acid target compound rather than a typical secondary-metabolite marker: because 5-HTP is already present in the seed in its final bioactive form, the process is built to protect yield and purity through gentle, controlled-temperature extraction, rapid clarification, and low-temperature vacuum concentration rather than pushing for aggressive extractive yield. Built in SS 316L with electropolished product-contact surfaces, closed-loop solvent recovery, PLC-based automation and full batch documentation, each plant is delivered as a commissioned turnkey system engineered to the declared 5-HTP By HPLC specification, with process parameters and drying conditions tuned to minimise degradation of this heat- and light-sensitive amino acid across the full 20-99% grade range.
Technical Specifications
| Product | Griffonia simplicifolia Extraction Plant |
|---|---|
| Botanical Name | Griffonia simplicifolia |
| Raw Material | Dried Griffonia simplicifolia seeds |
| Plant Part | Seed |
| Extract Type | Standardised dry extract (powder) |
| Standardisation | 5-HTP By HPLC 20% to 99% |
| Extraction Method | Controlled aqueous / hydro-alcoholic extraction (closed, jacketed SS 316L extractors) |
| Product-contact Material | SS 316L, electropolished, CIP-cleanable |
| Filtration System | Plate-and-frame filter press with cartridge polish filtration |
| Concentration System | Low-temperature falling-film / vacuum evaporator with closed-loop solvent recovery |
| Drying System | Vacuum tray dryer or spray dryer with light- and heat-protected handling |
| Automation | PLC-SCADA with recipe management, batch traceability and production reporting |
| Plant Capacity | Configured to requirement |
| Utility Requirements | Steam, chilled/cooling water, compressed air, soft water, power (project-specific) |
| Compliance | GMP, HACCP hygienic design; full documentation for qualification |
| Final Product Form | Free-flowing standardised extract powder |
Plant Capacities
| Plant Scale | Seed Throughput | Typical Use |
|---|---|---|
| Pilot | Configured to your feedstock and trial plan | Product development, parameter validation |
| Semi-Commercial | Configured between pilot and commercial scale | Contract manufacturing, scale-up trials |
| Commercial | Configured to raw-material supply and confirmed buyer volume | Export-grade continuous production |
Capacity is configured to raw-material supply and confirmed buyer volume; we recommend a pilot plant to validate parameters before scaling, given 5-HTP's sensitivity to temperature and processing time.
Manufacturing Process
Raw Material Cleaning & Size Reduction
Dried Griffonia simplicifolia seeds are cleaned to remove pods, husk fragments and foreign matter, then milled to a uniform particle size that exposes the seed's internal 5-HTP content to solvent without generating excess fines that slow downstream filtration.
Controlled Extraction
Milled seed is charged into closed, jacketed SS 316L extraction vessels and extracted with a controlled aqueous or hydro-alcoholic solvent system at moderated temperature, since 5-HTP is present in the seed as a free, already-formed amino acid and does not require prolonged or high-temperature extraction to release.
Solid-Liquid Separation & Filtration
The extract slurry is clarified through a plate-and-frame filter press followed by cartridge polish filters to remove seed fibre and residual pigment ahead of concentration.
Low-Temperature Vacuum Concentration
The filtered miscella is concentrated in a falling-film / vacuum evaporator under reduced pressure and closely controlled, moderated temperature to protect the heat- and light-sensitive 5-HTP molecule from oxidative degradation.
Solvent Recovery
A closed-loop recovery system condenses, purifies and recycles the recovered solvent back into production.
HPLC Standardisation
The concentrate is assayed by HPLC and adjusted to the declared specification — 5-HTP By HPLC within the 20% to 99% range — before drying.
Protected Drying & Quality Control
The standardised extract is vacuum-tray or spray dried under light- and heat-protected handling to a free-flowing powder, then released after HPLC assay, residual-solvent, heavy-metal, microbial, and moisture testing with full certificate-of-analysis documentation.
Major Plant Equipment
- Raw material cleaning system
- Hammer mill / seed mill (size reduction)
- Stainless-steel controlled-extraction vessels (jacketed, SS 316L)
- Solvent storage tanks
- Solvent transfer pumps
- Plate heat exchangers
- Plate-and-frame filter press / pressure leaf filter
- Cartridge polish filters
- Low-temperature falling-film / vacuum evaporator
- Closed-loop solvent recovery system
- Condensers & vacuum pumps
- Vacuum tray dryer / spray dryer (light- and heat-protected)
- CIP (clean-in-place) system
- Storage tanks & finished-product tanks
- PLC-SCADA control panel, electrical MCC & instrumentation
Plant Output
From Plant to Product
Griffonia simplicifolia Extract
This botanical is also in the product range of Sureka Life Sciences, our sister concern in botanical ingredients.
Applications
- Nutraceutical ingredient supply for mood- and sleep-support supplement formulations (as a serotonin-precursor ingredient category)
- High-purity 5-HTP API-grade ingredient manufacturing
- Capsule and tablet supplement manufacturing
- Functional food and beverage ingredient applications
- Pharmaceutical standardised ingredient supply
- Export to regulated-market dietary-supplement ingredient buyers
- Combination formulations with other calming or sleep-support botanicals
Key Features
GMP Hygienic SS 316L Construction
Electropolished SS 316L product-contact surfaces use GMP hygienic design, with CIP operation between batches.
Closed-Loop Solvent Recovery
Integrated recovery returns solvent for reuse each batch.
Low-Temperature Processing for a Sensitive Amino Acid
Extraction, concentration and drying stages are run at moderated temperatures throughout, since 5-HTP is a heat- and light-sensitive free amino acid already present in the seed rather than a stable secondary metabolite.
HPLC-Verified Standardisation Across a Wide Range
In-process and batch-release HPLC assay are used to check the finished extract against its declared 5-HTP band, from 20% up to 99% for API-grade output.
Integrated Protected Drying
A matched vacuum-tray or spray dryer with light- and heat-protected handling produces a free-flowing, low-moisture powder ready for encapsulation and blending.
Scalable Batch Capacity
Plants are configured to requirement from pilot scale upward, with modular expansion.
Frequently Asked Questions
Does Mechotech supply the complete machinery for Griffonia simplicifolia?
What specification can the Griffonia simplicifolia plant achieve?
Why is Griffonia simplicifolia seed a distinctive raw material?
Is Hydroxin (95% 5-HTP) covered on this page?
What extraction method is used, and how much solvent is recovered?
What production capacities are available for the Griffonia simplicifolia plant?
Which industries use Griffonia simplicifolia extract?
Ready to discuss your project?
Get a free quote and technical consultation from our engineering team.