Cissus Quadrangularis Extract
Cissus Quadrangularis Extract
Purity Levels
20% 3-ketosterones by Gravimetry
Mechotech designs and manufactures turnkey herbal extraction plants for Cissus quadrangularis (Hadjod), processing the fleshy, succulent stem — the medicinal part of this vine — into an extract standardised to 20% 3-ketosterones by Gravimetry. 3-ketosterones are a documented steroidal compound class concentrated in the stem, and the extract is a recognised ingredient in bone-health, joint-health, and sports-nutrition category products, including fracture-support and weight-management formulations in the traditional and modern nutraceutical markets. We supply the complete machinery — stem cleaning, size reduction, extraction, filtration, concentration and drying — to convert Cissus quadrangularis stem into a consistent extract for the nutraceutical, pharmaceutical, and Ayurvedic manufacturing industries.
Mechotech's Cissus quadrangularis plant is engineered around the specific chemistry and raw-material form of this succulent vine: because the medicinal stem is fleshy and moisture-rich rather than a dry leaf or root, the line includes dedicated pre-drying and size-reduction stages sized for succulent plant material ahead of solvent extraction. The finished extract is standardised by gravimetric assay — a weight-based quantification method appropriate for the mixed 3-ketosterone/steroidal compound class, where a single defined HPLC marker peak is not the industry-standard approach. Built in SS 316L with integrated solvent recovery, automation, and full documentation, each plant is delivered as a commissioned turnkey system engineered to the 20% 3-ketosterones by Gravimetry specification. Any health-category language used in connection with this extract (bone health, joint health, sports nutrition) refers to established nutraceutical structure/function product categories, not medical claims.
Technical Specifications
| Product | Cissus Quadrangularis Extract Plant |
|---|---|
| Botanical Name | Cissus quadrangularis |
| Raw Material | Fresh or dried Cissus quadrangularis stem |
| Plant Part | Stem (succulent vine segment) |
| Extract Type | Standardised dry extract (powder) |
| Standardisation | 20% 3-ketosterones by Gravimetry |
| Extraction Method | Aqueous / hydro-alcoholic extraction (closed, jacketed SS 316L extractors) |
| Product-contact Material | SS 316L, electropolished, CIP-cleanable |
| Pre-treatment | Stem cleaning, slicing and pre-drying (sized for succulent, moisture-rich raw material) |
| Filtration System | Plate-and-frame filter press with cartridge polish filtration |
| Concentration System | Falling-film / vacuum evaporator with closed-loop solvent recovery |
| Assay Method | Gravimetric assay (weight-based quantification of the 3-ketosterone/steroidal fraction) |
| Drying System | Spray dryer or vacuum tray dryer |
| Automation | PLC-SCADA with recipe management, batch traceability and production reporting |
| Plant Capacity | Configured to requirement |
| Utility Requirements | Steam, chilled/cooling water, compressed air, soft water, power (project-specific) |
| Compliance | GMP, HACCP hygienic design; full documentation for qualification |
| Final Product Form | Free-flowing standardised extract powder |
Plant Capacities
| Plant Scale | Stem Throughput | Typical Use |
|---|---|---|
| Pilot | Configured to your feedstock and trial plan | Product development, gravimetric-yield parameter validation |
| Semi-Commercial | Configured between pilot and commercial scale | Contract manufacturing, scale-up trials |
| Commercial | Configured to raw-material supply and confirmed buyer volume | Export-grade continuous production for bone-health and sports-nutrition buyers |
Capacity is configured to raw-material supply and confirmed buyer volume; we recommend a pilot plant to validate 3-ketosterone recovery parameters before scaling.
Manufacturing Process
Stem Reception & Cleaning
Fresh or dried Cissus quadrangularis stem segments are authenticated, cleaned of soil and foreign matter, and tested for moisture — a key control point given the stem's naturally succulent, moisture-rich tissue.
Slicing & Size Reduction
Cleaned stem is sliced and reduced to a uniform particle size, with pre-drying where required, to maximise solvent contact with the fleshy vine tissue before extraction.
Aqueous / Hydro-Alcoholic Extraction
Prepared stem material is extracted with water or a controlled hydro-alcoholic solvent system in closed, jacketed SS 316L extractors under regulated temperature and multiple cycles to recover the 3-ketosterone/steroidal fraction.
Filtration
The extract (miscella) is clarified through a plate-and-frame filter press followed by cartridge polish filters to remove fibrous stem residue.
Concentration & Solvent Recovery
The miscella is concentrated in a falling-film / vacuum evaporator with closed-loop solvent recovery through the condenser return system.
Gravimetric Standardisation
The concentrate is assayed gravimetrically — by weight-based quantification of the isolated steroidal/3-ketosterone fraction, the appropriate method for this mixed compound class — and adjusted to the declared 20% 3-ketosterones by Gravimetry specification before drying.
Drying & Quality Control
The standardised Cissus quadrangularis extract is spray- or vacuum-dried, then released after gravimetric assay, residual-solvent, heavy-metal, microbial, and moisture testing with full certificate-of-analysis documentation.
Major Plant Equipment
- Stem cleaning and slicing system
- Pre-drying unit (for succulent stem material)
- Stainless-steel aqueous/hydro-alcoholic extraction vessels (jacketed, SS 316L)
- Solvent storage tanks
- Solvent transfer pumps
- Plate-and-frame filter press / pressure leaf filter
- Cartridge polish filters
- Falling-film / vacuum evaporator
- Closed-loop solvent recovery system
- Condensers & vacuum pumps
- Gravimetric assay / QC laboratory equipment
- Spray dryer / vacuum tray dryer
- CIP (clean-in-place) system
- Storage tanks & finished-product tanks
- PLC-SCADA control panel, electrical MCC & instrumentation
Plant Output
Applications
- Bone-health nutraceutical capsule and tablet formulations
- Joint-health and mobility-support supplement blends
- Sports-nutrition and weight-management category products
- Pharmaceutical standardised ingredient supply
- Ayurvedic and traditional medicine preparations (Hadjod formulations)
- Export to regulated-market ingredient buyers
Key Features
GMP Hygienic SS 316L Construction
Electropolished SS 316L product-contact surfaces use GMP hygienic design, with CIP operation between batches.
Succulent-Stem Pre-Treatment
Dedicated slicing and pre-drying stages are sized for Cissus quadrangularis's fleshy, moisture-rich stem tissue — a genuinely different raw-material handling profile from dry leaf, root or bark botanicals.
Gravimetric Assay Capability
In-process and batch-release gravimetric assay correctly quantifies the mixed 3-ketosterone/steroidal compound class, rather than relying on a single HPLC marker peak.
Closed-Loop Solvent Recovery
Integrated recovery returns solvent for reuse each batch, reducing fresh-solvent consumption.
Integrated Drying
A matched spray/vacuum dryer produces a free-flowing, low-moisture powder ready for encapsulation and blending.
Scalable Batch Capacity
Plants are configured to requirement from pilot scale upward, with modular expansion.
Frequently Asked Questions
Does Mechotech supply the complete machinery for Cissus Quadrangularis Extract?
What specification can the Cissus Quadrangularis Extract plant achieve?
Why is gravimetric assay used for Cissus quadrangularis instead of HPLC?
What plant part of Cissus quadrangularis is used, and why does it need special handling?
What applications is Cissus quadrangularis extract used for?
What production capacities are available for the Cissus Quadrangularis Extract plant?
Which industries use the Cissus Quadrangularis Extract plant, and does the plant support GMP qualification?
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