Ginkgo Biloba
Ginkgo Biloba
Purity Levels
Flavone Glycosides and Terpene Lactones
Extraction Technologies
Mechotech designs and manufactures turnkey Ginkgo Biloba extraction plants that convert dried Ginkgo Biloba leaves into a standardised extract rich in flavone glycosides and terpene lactones (ginkgolides and bilobalide), while keeping ginkgolic acids within pharmacopeial limits. We supply the complete line — leaf preparation, hydro-alcoholic extraction, membrane clarification, solvent recovery, adsorption-resin purification, standardisation and spray drying — as a single turnkey system for the pharmaceutical, nutraceutical, food, and fragrance industries. Candidate extraction technologies for flavone glycosides: Counter-Current Extraction (CCE), Ultrasound-Assisted Extraction (UAE), Hybrid Extraction and Microwave-Assisted Extraction (MAE) (4 in total).
Mechotech's Ginkgo Biloba plant is engineered around the real processing chemistry of the leaf: hydro-alcoholic extraction recovers the flavone glycosides and terpene lactones, while membrane clarification and selective adsorption-resin purification enrich these actives and strip out undesirable ginkgolic acids to pharmacopeial limits (typically below 5 ppm). Built in SS 316L with integrated solvent recovery, automation, and full documentation, each plant is delivered as a commissioned turnkey system configured to the declared Flavone Glycosides and Terpene Lactones specification — 24% flavone glycosides / 6% terpene lactones profile, or a custom standardisation to your requirement.
Technical Specifications
| Product | Ginkgo Biloba Extract — Flavone Glycosides & Terpene Lactones |
|---|---|
| Botanical Name | Ginkgo biloba |
| Feedstock | Ginkgo leaves |
| Part / Feed Form | Leaves |
| Target Extract | Flavone glycosides |
| Extract Type | Standardised hydro-alcoholic extract, spray-dried powder |
| Standardisation | Standardised flavone glycosides & terpene lactones (24% / 6%); ginkgolic acids reduced to pharmacopeial limits |
| Extraction Method | Counter-current, UAE, Hybrid, MAE |
| Technology Count | 4 |
| Extraction Conditions | Hydro-alcoholic extraction (closed jacketed extractors, multiple cycles) |
| Purification | Membrane clarification (micro/ultrafiltration) + selective adsorption-resin enrichment (ginkgolic-acid reduction) |
| Product-contact Material | SS 316L, electropolished, CIP/SIP-cleanable |
| Filtration System | Multi-stage pressure filtration with membrane clarification |
| Concentration System | Vacuum evaporator with integrated solvent recovery |
| Drying System | Spray dryer |
| Automation | Configurable — manual, semi-automatic or fully automatic PLC-SCADA (recipe-based) |
| Utility Requirements | Steam, chilled/cooling water, compressed air, soft/RO water, nitrogen, power (project-specific) |
| Compliance | GMP hygienic design; full documentation for qualification |
| Final Product Form | Free-flowing standardised powder |
| Plant Capacity | Reference project: 15 MT/day of ginkgo leaves (see the Ginkgo Biloba Extraction Plant case study) |
Plant Capacities
| Plant Scale | Raw Material Throughput | Typical Use |
|---|---|---|
| Pilot | Configured to your feedstock and trial plan | Product development, parameter validation |
| Semi-Commercial | Configured between pilot and commercial scale | Contract manufacturing, scale-up trials |
| Commercial | Reference project: 15 MT/day of ginkgo leaves | Commercial production at confirmed buyer volume |
The commercial figure is the reference project described in the Ginkgo Biloba Extraction Plant case study. Capacity is configured to raw-material supply and confirmed buyer volume; we recommend a pilot plant to validate process parameters before scaling.
Manufacturing Process
Each extraction method follows a different process — pick a method to see its steps.
Raw-Material Preparation
Ginkgo leaves are cleaned and size-reduced so flavone glycosides can be reached by the extraction medium; particle size and moisture are set during process development.
Counter-Current Loading
Prepared ginkgo leaves are fed into a multi-stage solid–liquid counter-current extractor where fresh ethanol/water or a suitable food-grade solvent meets the most-depleted material.
Counter-Current Extraction
Solvent flows against the solids across stages to draw out flavone glycosides; bed flow and fines management are verified during pilot work.
Extract (Miscella) Collection
The flavone glycosides-bearing miscella is collected from the fresh-feed end while spent solids are discharged from the solvent-entry end.
Concentration & Solvent Recovery
Solvent is removed from the clarified flavone glycosides-bearing extract under vacuum and returned through a solvent-recovery loop; recovery performance is confirmed at pilot scale.
Standardisation & Drying
The flavone glycosides extract is assayed against the declared target specification and dried or supplied as a concentrate, according to the requirement.
Raw-Material Preparation
Ginkgo leaves are cleaned and size-reduced so flavone glycosides can be reached by the extraction medium; particle size and moisture are set during process development.
Slurrying
Prepared ginkgo leaves are slurried with ethanol/water or water in the extraction vessel.
Ultrasonic Cavitation
Ultrasound creates cavitation that disrupts the plant matrix and speeds release of flavone glycosides; probe intensity, temperature and filtration behaviour are piloted.
Separation
Spent solids are separated by filtration or centrifugation and the extract is clarified before concentration.
Concentration & Solvent Recovery
Solvent is removed from the clarified flavone glycosides-bearing extract under vacuum and returned through a solvent-recovery loop; recovery performance is confirmed at pilot scale.
Standardisation & Drying
The flavone glycosides extract is assayed against the declared target specification and dried or supplied as a concentrate, according to the requirement.
Raw-Material Preparation
Ginkgo leaves are cleaned and size-reduced so flavone glycosides can be reached by the extraction medium; particle size and moisture are set during process development.
Stage Sequence Selection
A deliberate combined extraction train is used: the sequence of stages is selected for flavone glycosides in pilot screening and each stage is designed separately.
First Assisted Stage
The first stage releases flavone glycosides from the prepared feed under controlled conditions set for that stage.
Second / Combined Stage
The second stage completes recovery of flavone glycosides from the partially extracted material; stage conditions are optimised separately.
Separation & Concentration
Spent solids are removed and the combined extract is clarified and concentrated; solvent is recovered where a solvent is used.
Standardisation & Drying
The flavone glycosides extract is assayed against the declared target specification and dried or supplied as a concentrate, according to the requirement.
Raw-Material Preparation
Ginkgo leaves are cleaned and size-reduced so flavone glycosides can be reached by the extraction medium; particle size and moisture are set during process development.
Medium Mixing
Prepared ginkgo leaves are mixed with ethanol/water or water in the microwave extraction vessel.
Microwave Heating & Extraction
Controlled microwave heating drives flavone glycosides out of the prepared feed in a short cycle; heating, moisture, solvent safety and temperature-sensitive targets are controlled, with limits set during process development and pilot validation.
Separation
Spent solids are separated by filtration or centrifugation and the extract is clarified before concentration.
Concentration & Solvent Recovery
Solvent is removed from the clarified flavone glycosides-bearing extract under vacuum and returned through a solvent-recovery loop; recovery performance is confirmed at pilot scale.
Standardisation & Drying
The flavone glycosides extract is assayed against the declared target specification and dried or supplied as a concentrate, according to the requirement.
Major Plant Equipment
- Raw material cleaning system
- Grinding mill
- Stainless-steel jacketed extraction vessels
- Solvent storage tanks
- Pressure leaf filters
- Membrane filtration system (micro/ultrafiltration)
- Vacuum evaporators
- Solvent recovery & condenser system
- Adsorption resin purification columns
- Spray dryer
- Ribbon blender
- Product storage silos
- CIP/SIP system
- PLC-SCADA automation panel, electrical MCC & instrumentation
Plant Output
Case Study
Ginkgo Biloba Extraction Plant — 24/6 Standardised Extract
See how this plant was engineered and delivered for a real project.
From Plant to Product
Ginkgo Biloba Extract
This botanical is also in the product range of Sureka Life Sciences, our sister concern in botanical ingredients.
Applications
- Memory-support and cognitive-health supplement formulations
- Circulatory-health nutraceutical formulations
- Nutraceutical capsule, tablet, and supplement manufacturing
- Pharmaceutical standardised ingredient supply
- Cosmetic and personal care active ingredients
- Export to regulated-market ingredient buyers
Key Features
GMP Hygienic SS 316L Construction
Electropolished SS 316L product-contact surfaces use GMP hygienic design, with CIP operation between batches.
Closed-Loop Solvent Recovery
Integrated recovery returns solvent per batch for reuse.
Standardised to Specification
In-process and batch-release assay are used to check the finished Ginkgo Biloba extract against its declared specification (Flavone Glycosides and Terpene Lactones).
Integrated Drying
A matched spray/vacuum dryer produces a free-flowing, low-moisture powder ready for encapsulation and blending.
Scalable Batch Capacity
Plants are configured to raw-material supply and confirmed buyer volume; the reference project processes 15 MT/day of ginkgo leaves.
Frequently Asked Questions
Does Mechotech supply the complete machinery for Ginkgo Biloba?
What specification can the Ginkgo Biloba plant achieve?
Does Mechotech offer plants standardised to a single marker compound instead of both actives?
How are ginkgolic acids controlled during extraction?
What production capacities are available for the Ginkgo Biloba plant?
Which industries use the Ginkgo Biloba plant?
What is a ginkgo leaf extraction plant for flavone glycosides?
Which plant part or feed form does the ginkgo leaf plant process?
Which extraction technologies are suitable for ginkgo leaves?
How does the ginkgo leaf extraction process work?
What equipment does the ginkgo leaf extraction plant include?
Which related Mechotech extraction pages cover the same material or target?
What does a Ginkgo Biloba extraction plant cost, and how do I choose the right configuration?
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